AKUdatabase


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Mutations Mus musculus


This table was constructed based in the publications from Markus Grompe's laboratory Manning et al., 1999 and Manning et al., 1999.

Name

Mutation

Nucleotide change1

Amino Acid change/Predicted Consequence

DelV265

Deletion

c.966DelTCG

Deletion of V265

T267G

Missense

c.970GAC® TGG

Thr267Gly

W268G

Missense

c.974T® G

Trp268Gly

K286E

Missense

c.998A® G

Lys268Glu

D294N

Missense

c.1052G® A

Asp294Asn

T328P

Missense

c.1154A® C

Thr328Pro

T328I

Missense

c.1155C® T

Thr328Ile

R330G

Missense

c.1160A® G

Arg330Gly

E341D

Missense

c.1195G® T

Glu341Asp

c.1253Del31bp

Deletion

c.1253Del31bp

Truncation after G360

c.1261-1287 duplication

Duplication

c.1261-1287 duplication

Frameshift after G372

H371D

Missense

c.1283C® G

His371Asp

G372S

Missense

c.1286G® A

Gly372Ser

H371fs

Frameshift

c.1287DelG

Frameshift after H371

P372fs

Frameshift

c.1292DelG

Frameshift after P372

L386fs

Frameshift

c.1330DelC

Frameshift after L386

A392fs

Frameshift

c.1351DelC

Frameshift after A392

D393fs

Frameshift

c.1351InsT

Frameshift after D393

M396fs

Frameshift

c.1363InsCG

Frameshift after M369

F398fs

Frameshift

c.1367DelAT

Frameshift after F398

S403X

Nonsense

c.1377DelCTTC

Stop at S403

DelL429-S437

Deletion

c.1458Del27bp

Deletion L429-S437

1) Nucleotide 1 is the first base of the published M. musculus cDNA sequence: U58988.